BDBM50091283 CHEMBL3582232

SMILES C(N1CCCCC1)c1ccc(cc1)-c1cnc2[nH]c3cnc(cc3c2c1)-c1cncnc1

InChI Key InChIKey=CJPWVSWHUPXWHU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091283   

TargetSerine/threonine-protein kinase Chk1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091283(CHEMBL3582232)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091283(CHEMBL3582232)
Affinity DataEC50:  163nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091283(CHEMBL3582232)
Affinity DataIC50: 266nMAssay Description:Inhibition of human acetylcholine esterase by horseradish peroxidase-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed