BDBM500913 (R)-7-((5-(3- ((dimethylamino)- methyl)-3- hydroxypiperidin- 1-yl)pyridin-2- yl)amino)-4- (8-fluoro-7- methylimidazo [1,2-a]pyridin- 3-yl)isoindolin- 1-one::US11021481, Compound I-577::US11078201, Compound I-577::US11548890, Compound I-577
SMILES CN(C)C[C@]1(O)CCCN(C1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnc3c(F)c(C)ccn23)nc1
InChI Key InChIKey=VCZQMRLURQOOCK-GDLZYMKVSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 500913
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair