BDBM50091308 CHEMBL3582217

SMILES C(N1CCCCC1)c1ccc(cc1)-c1cnc2[nH]c3cnccc3c2c1

InChI Key InChIKey=AGJHYDCWZUUFAE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091308   

TargetSerine/threonine-protein kinase Chk1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091308(CHEMBL3582217)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50091308(CHEMBL3582217)
Affinity DataEC50:  1.92E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details Article
PubMed