BDBM500915 (S)-4-(8-fluoro-7- methylimidazo [1,2-a]pyridin- 3-yl)-7-((5-(2- (methoxymeth- yl)morpho- lino)pyridin-2- yl)amino)isoin- dolin-1-one::US11021481, Compound I-579::US11078201, Compound I-579::US11548890, Compound I-579

SMILES COC[C@@H]1CN(CCO1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnc3c(F)c(C)ccn23)nc1

InChI Key InChIKey=QIBCROVDHLYOAV-SFHVURJKSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500915   

LigandPNGBDBM500915((S)-4-(8-fluoro-7- methylimidazo [1,2-a]pyridin- 3...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500915((S)-4-(8-fluoro-7- methylimidazo [1,2-a]pyridin- 3...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500915((S)-4-(8-fluoro-7- methylimidazo [1,2-a]pyridin- 3...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500915((S)-4-(8-fluoro-7- methylimidazo [1,2-a]pyridin- 3...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM500915((S)-4-(8-fluoro-7- methylimidazo [1,2-a]pyridin- 3...)
Affinity DataIC50: <100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent