BDBM50091742 3-Ethynyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-ethyl)-piperidin-1-yl]-hexanoic acid::CHEMBL444573

SMILES OC(=O)CC(CCCN1CCC[C@@H](CCC2CCNCC2)C1=O)C#C

InChI Key InChIKey=KQRSYIYBILSZCZ-DAFXYXGESA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091742   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091742(3-Ethynyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-ethyl)-...)
Affinity DataIC50:  51nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091742(3-Ethynyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-ethyl)-...)
Affinity DataKd:  3.10E+3nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091742(3-Ethynyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-ethyl)-...)
Affinity DataKd:  9nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed