BDBM50091746 (E)-(R)-3-Methyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-ethyl)-piperidin-1-yl]-hex-4-enoic acid::CHEMBL61353

SMILES C[C@H](CC(O)=O)\C=C\CN1CCC[C@@H](CCC2CCNCC2)C1=O

InChI Key InChIKey=HOXBDAPDLBOLFT-FCSRKSAXSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091746   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091746((E)-(R)-3-Methyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-...)
Affinity DataKd:  12nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091746((E)-(R)-3-Methyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-...)
Affinity DataKd:  2.30E+3nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091746((E)-(R)-3-Methyl-6-[(R)-2-oxo-3-(2-piperidin-4-yl-...)
Affinity DataIC50:  57nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed