BDBM50091800 2-amino-4-methylpyridine::4-METHYLPYRIDIN-2-AMINE::4-METHYLPYRIDIN-2-AMINE, 6::4-Methyl-pyridin-2-ylamine::CHEMBL40833

SMILES Cc1ccnc(N)c1

InChI Key InChIKey=ORLGLBZRQYOWNA-UHFFFAOYSA-N

Data  13 IC50

PDB links: 3 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50091800   

TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  120nMpH: 7.0 T: 37°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  320nMpH: 7.0 T: 37°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  160nMpH: 7.0 T: 37°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  72nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed