BDBM50092218 CHEMBL3581264

SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccc3ccccc3c1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc1ccc(O)cc1)NC2=O

InChI Key InChIKey=AVNDVFCGYOONJV-UHFFFAOYSA-N

Data  2 IC50  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50092218   

TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  74nMAssay Description:Agonist activity at CXCR7 (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rluc assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  79nMAssay Description:Agonist activity at CXCR7 (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rluc assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  190nMAssay Description:Agonist activity at wild type CXCR7 (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rluc a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  190nMAssay Description:Agonist activity at wild type CXCR7 (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rluc a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  360nMAssay Description:Agonist activity at CXCR7 S198R mutant (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rlu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  360nMAssay Description:Agonist activity at CXCR7 S198R mutant (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rlu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at CXCR7 D275N mutant (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rlu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of [125I]SDF-1alpha binding to CXCR7 (unknown origin) expressed in CHO cell membranes incubated for 1 hr by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at CXCR7 D275N mutant (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rlu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at CXCR7 D179N mutant (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rlu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at CXCR7 D179N mutant (unknown origin) expressed in HEK293E cells co-transfected with receptor-eYFP construct and beta-arrestin2-Rlu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092218(CHEMBL3581264)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [125I]SDF-1alpha binding to CXCR4 (unknown origin) expressed in HEK293 cell membranes incubated for 1 hr by radioligand displacement as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed