BDBM50092631 4-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-[3-iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)-benzyl]-pyrrolidin-2-one::CHEMBL126587

SMILES COc1ccc(cc1OC1CCCC1)C1CN(Cc2cc(I)cc(c2)C2(N=N2)C(F)(F)F)C(=O)C1

InChI Key InChIKey=ROWXAVVLUNUZBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092631   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092631(4-(3-Cyclopentyloxy-4-methoxy-phenyl)-1-[3-iodo-5-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human PDE4A expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed