BDBM50092687 CHEMBL434817::N,N-Diethyl-4-[(3-methoxy-phenyl)-(2,2,5-trimethyl-piperazin-1-yl)-methyl]-benzamide

SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1CC(C)NCC1(C)C)c1cccc(OC)c1

InChI Key InChIKey=YLSDZONXUSTQQM-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092687   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092687(N,N-Diethyl-4-[(3-methoxy-phenyl)-(2,2,5-trimethyl...)
Affinity DataIC50: 53nMAssay Description:Binding affinity against human opioid receptor delta 1 using [125I]-[D-Ala2]-deltorphin II as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092687(N,N-Diethyl-4-[(3-methoxy-phenyl)-(2,2,5-trimethyl...)
Affinity DataEC50:  273nMAssay Description:Agonist potency was measured using GTP gamma-[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092687(N,N-Diethyl-4-[(3-methoxy-phenyl)-(2,2,5-trimethyl...)
Affinity DataIC50: 284nMAssay Description:Binding affinity against cloned human Opioid receptor mu 1 using [125I]FK33824 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50092687(N,N-Diethyl-4-[(3-methoxy-phenyl)-(2,2,5-trimethyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against cloned human Opioid receptor kappa 1 using [125I]-D-Pro10-dynorphin A[1-11] as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed