BDBM50092928 1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dichloro-phenylsulfanyl)-3-nitro-phenyl]-propenone::CHEMBL130110
SMILES CC(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Sc2cccc(Cl)c2Cl)c(c1)[N+]([O-])=O
InChI Key InChIKey=LNUHEJIWTOBAQF-SOFGYWHQSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50092928
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Human)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(100-110)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(30-300)More data for this Ligand-Target Pair