BDBM50093042 CHEMBL74860::N-[3'-(6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-biphenyl-4-yl]-4-(3-hexyl-ureido)-benzenesulfonamide

SMILES CCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cccc(CC2NCCc3cc(O)c(O)cc23)c1

InChI Key InChIKey=QWPHHLLRPMQBBN-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50093042   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093042(N-[3'-(6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataEC50:  600nMAssay Description:Inhibitory activity against human beta-3 adrenergic receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093042(N-[3'-(6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataEC50: >1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against human beta-2 adrenergic receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093042(N-[3'-(6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataEC50: >1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against human beta-1 adrenergic receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093042(N-[3'-(6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against CHO cells expressing human Beta-2 adrenergic receptor with [125I]-iodocyanopindololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093042(N-[3'-(6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for its inhibitory activity against CHO cells expressing the cloned human beta-1 adrenergic receptor (AR) in the presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed