BDBM50093144 CHEMBL46120::N-(4-Guanidino-benzyl)-N'-(4-{[2-(4-guanidino-benzylcarbamoyl)-acetylamino]-methyl}-benzyl)-malonamide

SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6]-c2ccc(-[#6]-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6]-c3ccc(cc3)\[#7]=[#6](\[#7])-[#7])cc2)cc1

InChI Key InChIKey=OUJFUEBLAXEVRB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093144   

TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093144(N-(4-Guanidino-benzyl)-N'-(4-{[2-(4-guanidino-benz...)
Affinity DataKi:  680nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093144(N-(4-Guanidino-benzyl)-N'-(4-{[2-(4-guanidino-benz...)
Affinity DataKi:  7.30E+4nMAssay Description:Inhibitory potency against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093144(N-(4-Guanidino-benzyl)-N'-(4-{[2-(4-guanidino-benz...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory potency against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093144(N-(4-Guanidino-benzyl)-N'-(4-{[2-(4-guanidino-benz...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory potency against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed