BDBM50093146 CHEMBL77521::N-(4-Aminomethyl-benzyl)-N'-(4-{[2-(4-aminomethyl-benzylcarbamoyl)-acetylamino]-methyl}-benzyl)-malonamide

SMILES NCc1ccc(CNC(=O)CC(=O)NCc2ccc(CNC(=O)CC(=O)NCc3ccc(CN)cc3)cc2)cc1

InChI Key InChIKey=ICJRTFAHVMZUFX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093146   

TargetTryptase beta-2(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093146(N-(4-Aminomethyl-benzyl)-N'-(4-{[2-(4-aminomethyl-...)
Affinity DataKi:  150nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093146(N-(4-Aminomethyl-benzyl)-N'-(4-{[2-(4-aminomethyl-...)
Affinity DataKi:  3.17E+5nMAssay Description:Inhibitory potency against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093146(N-(4-Aminomethyl-benzyl)-N'-(4-{[2-(4-aminomethyl-...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory potency against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093146(N-(4-Aminomethyl-benzyl)-N'-(4-{[2-(4-aminomethyl-...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory potency against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed