BDBM50093555 CHEMBL3585757

SMILES CCOc1ccc(cc1-c1nnc2n(nc(C)c2n1)-c1ccc(Cl)cc1)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=YXOGKIQQUJWBKL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093555   

TargetCarbonic anhydrase 12(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50093555(CHEMBL3585757)
Affinity DataKi:  82nMAssay Description:Inhibition of human carbonic anhydrase-12 pre-incubated for 15 mins by stopped-flow CO2 hydration assay based Lineweaver-Burk plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50093555(CHEMBL3585757)
Affinity DataKi:  403nMAssay Description:Inhibition of human carbonic anhydrase-9 pre-incubated for 15 mins by stopped-flow CO2 hydration assay based Lineweaver-Burk plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50093555(CHEMBL3585757)
Affinity DataKi:  854nMAssay Description:Inhibition of human carbonic anhydrase-1 pre-incubated for 15 mins by stopped-flow CO2 hydration assay based Lineweaver-Burk plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Siedlce University of Natural Sciences and Humanities

Curated by ChEMBL
LigandPNGBDBM50093555(CHEMBL3585757)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase-2 pre-incubated for 15 mins by stopped-flow CO2 hydration assay based Lineweaver-Burk plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed