BDBM50094499 2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile::CHEMBL141035

SMILES Clc1ccccc1N1CCN(Cc2cc3cc(ccc3[nH]2)C#N)CC1

InChI Key InChIKey=RALJYNLSBJABSL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094499   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094499(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-in...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094499(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-in...)
Affinity DataKi:  950nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2S expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094499(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-in...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094499(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-in...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094499(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-in...)
Affinity DataKi:  7.50E+3nMAssay Description:Displacement of [3H]SCH-23390 from Dopamine receptor D1 of bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed