BDBM50094534 1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-isoindole::1,3-bis(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-isoindole::CHEMBL441663

SMILES Fc1ccc(-c2[nH]c(-c3ccc(F)cc3)c3c2CCCC3)cc1

InChI Key InChIKey=PWORIKUKVBOCDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094534   

TargetProstaglandin G/H synthase 2(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50094534BDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50094534BDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50094534BDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed