BDBM50094621 CHEMBL143398::Phosphoric acid mono-[3-hydroxy-5-(5-hydroxymethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl] ester(HmdUMP)

SMILES C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)CO)COP(=O)(O)O)O

InChI Key InChIKey=WEBVWKFGRVLCNS-UHFFFAOYSA-N

Data  2 KI

PDB links: 10 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094621   

TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50094621(Phosphoric acid mono-[3-hydroxy-5-(5-hydroxymethyl...)
Affinity DataKi:  900nMAssay Description:Time-independent inhibition of thymidylate synthase from FdUrd-resistant L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50094621(Phosphoric acid mono-[3-hydroxy-5-(5-hydroxymethyl...)
Affinity DataKi:  3.70E+3nMAssay Description:Time-independent inhibition of thymidylate synthase from parenteral L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed