BDBM50094676 CHEMBL142936::Diethyl-[2-(1H-indol-3-yl)-ethyl]-amine::N,N-diethyl-2-(1H-indol-3-yl)ethanamine

SMILES CCN(CC)CCc1c[nH]c2ccccc12

InChI Key InChIKey=LSSUMOWDTKZHHT-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50094676   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094676(CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...)
Affinity DataKi:  47nMAssay Description:Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094676(CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...)
Affinity DataKi:  104nMAssay Description:Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094676(CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...)
Affinity DataKi:  133nMAssay Description:Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50094676(CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...)
Affinity DataKi:  575nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094676(CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...)
Affinity DataEC50:  680nMAssay Description:EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094676(CHEMBL142936 | Diethyl-[2-(1H-indol-3-yl)-ethyl]-a...)
Affinity DataEC50:  5.37E+3nMAssay Description:Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed