BDBM50095256 (6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-4-fluoro-phenyl)-amine::CHEMBL65250
SMILES COc1cc2ncnc(Nc3ccc(F)c(c3)C#C)c2cc1OC
InChI Key InChIKey=UEKLAZGZLXRYAO-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50095256
Affinity DataIC50: 4nMAssay Description:Inhibition of (EGFR) epidermal growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences
Curated by ChEMBL
University Institute of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for its concentration required to inhibit the rat liver F16BPaseMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences
Curated by ChEMBL
University Institute of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair