BDBM50095277 (6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-amine::CHEMBL1204261::CHEMBL294126

SMILES CCOc1cc2ncnc(Nc3cccc(F)c3)c2cc1OCC

InChI Key InChIKey=VIZJVXABYUPLHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095277   

TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277(CHEMBL294126 | CHEMBL1204261 | (6,7-Diethoxy-quina...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277(CHEMBL294126 | CHEMBL1204261 | (6,7-Diethoxy-quina...)
Affinity DataIC50: 8.17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095277(CHEMBL294126 | CHEMBL1204261 | (6,7-Diethoxy-quina...)
Affinity DataIC50: 9.20E+3nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed