BDBM50095295 CHEMBL3589083::US9278953, 2
SMILES Cn1ncc2c(Cl)cc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCCNC1=O
InChI Key InChIKey=ZUQBSULIDWEOEB-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50095295
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor by MicroBeta plate-based scintillation counting/SPA binding assayMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataKi: 3.60nM ΔG°: -11.5kcal/molepH: 7.4 T: 2°CAssay Description:Test compounds were half log serially diluted in 100% DMSO (J. T. Baker #922401). 1 uL of each compound was added to appropriate wells of a 384-well ...More data for this Ligand-Target Pair