BDBM50095483 3-Cyclohexylmethoxy-azetidine-1-carbonitrile::CHEMBL8726

SMILES N#CN1CC(C1)OCC1CCCCC1

InChI Key InChIKey=YQKMEJDAMLDEFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095483   

TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095483(3-Cyclohexylmethoxy-azetidine-1-carbonitrile | CHE...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095483(3-Cyclohexylmethoxy-azetidine-1-carbonitrile | CHE...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095483(3-Cyclohexylmethoxy-azetidine-1-carbonitrile | CHE...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed