BDBM50095494 CHEMBL8563::N-(1-Cyano-pyrrolidin-3-ylmethyl)-benzenesulfonamide

SMILES O=S(=O)(NCC1CCN(C1)C#N)c1ccccc1

InChI Key InChIKey=RUHJZXDUKDCUQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095494   

TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095494(N-(1-Cyano-pyrrolidin-3-ylmethyl)-benzenesulfonami...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095494(N-(1-Cyano-pyrrolidin-3-ylmethyl)-benzenesulfonami...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095494(N-(1-Cyano-pyrrolidin-3-ylmethyl)-benzenesulfonami...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed