BDBM50095576 1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl-imidazolidin-1-yl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL147005

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)n1c(O)cn(CCC)c1=O

InChI Key InChIKey=VPXAENCQUJDPFF-MAUKXSAKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095576   

TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095576(1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095576(1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -2 (gelatinase-A)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50095576(1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095576(1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl...)
Affinity DataIC50:  570nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50095576(1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095576(1-(4-Butoxy-benzenesulfonyl)-4-(2,5-dioxo-3-propyl...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase-13 (collagenase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed