BDBM50096188 3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-aza-bicyclo[3.2.1]octane; hydrochloride::CHEMBL559215

SMILES Clc1cccc(c1)C(OC1CC2CCC(C1)N2)c1ccccc1

InChI Key InChIKey=VBIBMSGIVNIIOD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50096188   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50096188(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-aza-bicyclo...)
Affinity DataKi:  26.2nMAssay Description:Binding affinity for dopamine transporter was determined in vitro in rat brain using [3H]WIN-35428 s radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50096188(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-aza-bicyclo...)
Affinity DataKi:  91.7nMAssay Description:Binding affinity for muscarinic m1 receptor was determined in vitro in rat brain using [3H]pirenzepine as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50096188(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-aza-bicyclo...)
Affinity DataKi:  508nMAssay Description:Binding affinity for norepinephrine transporter in rat brain using [3H]-nisoxatine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50096188(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-aza-bicyclo...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity for serotonin transporter was determined in vitro in rat brain using [3H]citalopram as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed