BDBM50096648 2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hydroxy-4-(4-oxo-4H-benzo[d][1,2,3]triazin-3-yl)-butyramide::CHEMBL100584

SMILES ONC(=O)C(CCn1nnc2ccccc2c1=O)COCCc1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=IFHBUYGFCSEHIF-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50096648   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human MMP9 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human MMP3 using (7-methoxycoumarine-4-yl)-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 as substrate by fluorometer ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human MMP2 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human MMP13 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 67nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant human MMP1 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed