BDBM50096667 3-(1-Benzyloxy-3-cyclopropyl-1-trifluoromethyl-prop-2-ynyl)-1H-quinolin-2-one::CHEMBL105863

SMILES FC(F)(F)C(OCc1ccccc1)(C#CC1CC1)c1cc2ccccc2[nH]c1=O

InChI Key InChIKey=BWWRQIOZJFXZDA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096667   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096667(3-(1-Benzyloxy-3-cyclopropyl-1-trifluoromethyl-pro...)
Affinity DataIC50: 36nMAssay Description:Inhibition of the NNRTI HIV-1 enzyme by 50% using enzyme assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed