BDBM50096672 3-(3-Cyclopropyl-1-cyclopropylmethoxy-1-trifluoromethyl-prop-2-ynyl)-5-ethyl-6-methyl-1H-pyridin-2-one::CHEMBL105400

SMILES CCc1cc(c(=O)[nH]c1C)C(OCC1CC1)(C#CC1CC1)C(F)(F)F

InChI Key InChIKey=DWVSHPRSOSSELY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096672   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096672(3-(3-Cyclopropyl-1-cyclopropylmethoxy-1-trifluorom...)
Affinity DataIC50: 188nMAssay Description:Inhibition of the NNRTI HIV-1 enzyme by 50% using enzyme assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed