BDBM50097234 (R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamino)butan-2-yl)carbamoyl)-6-phenylhexanoic acid::(R)-3-[(S)-2,2-Dimethyl-1-(pyridin-4-ylcarbamoyl)-propylcarbamoyl]-6-phenyl-hexanoic acid::CHEMBL345445

SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(O)=O)C(=O)Nc1ccncc1

InChI Key InChIKey=GBABKPSGHJLCTJ-WIYYLYMNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097234   

TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097234((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...)
Affinity DataIC50:  275nMAssay Description:Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097234((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097234((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...)
Affinity DataIC50:  275nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097234((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...)
Affinity DataIC50:  6.40nMAssay Description:Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed