BDBM50097238 (R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-2-methoxy-1-phenyl-ethylcarbamoyl)-2,2-dimethyl-propyl]-2-(3-phenyl-propyl)-succinamide::(R)-N4-hydroxy-N1-((S)-1-((R)-2-methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-yl)-2-(3-phenylpropyl)succinamide::CHEMBL152531

SMILES COC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(C)(C)C)c1ccccc1

InChI Key InChIKey=LYTGQQFBDSMLSD-GIFXNVAJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097238   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097238((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-2-methoxy-1-phen...)
Affinity DataIC50:  15nMAssay Description:Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097238((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-2-methoxy-1-phen...)
Affinity DataIC50:  22nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097238((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-2-methoxy-1-phen...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097238((R)-N*4*-Hydroxy-N*1*-[(S)-1-((R)-2-methoxy-1-phen...)
Affinity DataIC50:  22nMAssay Description:Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed