BDBM50097239 (R)-N*1*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethyl-propyl]-N*4*-hydroxy-2-(3-phenyl-propyl)-succinamide::(R)-N1-((S)-1-(benzhydrylamino)-3,3-dimethyl-1-oxobutan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide::CHEMBL436230

SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=HMXIGWYKQCGDNX-GGXMVOPNSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097239   

TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097239((R)-N*1*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50:  48nMAssay Description:Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097239((R)-N*1*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50:  414nMAssay Description:Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097239((R)-N*1*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50:  417nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097239((R)-N*1*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50:  414nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-2 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097239((R)-N*1*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50:  48nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097239((R)-N*1*-[(S)-1-(Benzhydryl-carbamoyl)-2,2-dimethy...)
Affinity DataIC50:  48nMAssay Description:Concentration required to inhibit the catalytic domain Matrix metalloprotease-3 using Nagase fluorogenic as a substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed