BDBM50097240 (R)-N*1*-((S)-1-Cyclohexylcarbamoyl-2,2-dimethyl-propyl)-N*4*-hydroxy-2-(3-phenyl-propyl)-succinamide::(R)-N1-((S)-1-(cyclohexylamino)-3,3-dimethyl-1-oxobutan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide::CHEMBL157112

SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC1CCCCC1

InChI Key InChIKey=WTMNDZGXJUPIBE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097240   

Target72 kDa type IV collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097240((R)-N1-((S)-1-(cyclohexylamino)-3,3-dimethyl-1-oxo...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097240((R)-N1-((S)-1-(cyclohexylamino)-3,3-dimethyl-1-oxo...)
Affinity DataIC50: 1.30nMAssay Description:Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097240((R)-N1-((S)-1-(cyclohexylamino)-3,3-dimethyl-1-oxo...)
Affinity DataIC50: 19nMAssay Description:Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097240((R)-N1-((S)-1-(cyclohexylamino)-3,3-dimethyl-1-oxo...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed