BDBM50097242 (R)-N*1*-((S)-1-tert-Butylcarbamoyl-2,2-dimethyl-propyl)-N*4*-hydroxy-2-(3-phenyl-propyl)-succinamide::(R)-N1-((S)-1-(tert-butylamino)-3,3-dimethyl-1-oxobutan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide::CHEMBL152592

SMILES CC(C)(C)NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(C)(C)C

InChI Key InChIKey=VHDLIHHMSRFRJB-IEBWSBKVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097242   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097242((R)-N*1*-((S)-1-tert-Butylcarbamoyl-2,2-dimethyl-p...)
Affinity DataIC50:  5.80nMAssay Description:Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097242((R)-N*1*-((S)-1-tert-Butylcarbamoyl-2,2-dimethyl-p...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097242((R)-N*1*-((S)-1-tert-Butylcarbamoyl-2,2-dimethyl-p...)
Affinity DataIC50:  21nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097242((R)-N*1*-((S)-1-tert-Butylcarbamoyl-2,2-dimethyl-p...)
Affinity DataIC50:  21nMAssay Description:Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed