BDBM50097248 (R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-2-isobutyl-succinamide::CHEMBL151741

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CCc2ccccc12

InChI Key InChIKey=FGDQQAHGMHOQDV-NGXZDTIWSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50097248   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50097248((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50097248((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...)
Affinity DataKi:  24nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50097248((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...)
Affinity DataKi:  30nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50097248((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...)
Affinity DataKi:  30nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097248((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-indan-1-ylcarbam...)
Affinity DataKi:  93nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed