BDBM50097253 (R)-3-(((S)-3,3-dimethyl-1-oxo-1-((S)-1-phenylethylamino)butan-2-yl)carbamoyl)-6-phenylhexanoic acid::(R)-3-[(S)-2,2-Dimethyl-1-((S)-1-phenyl-ethylcarbamoyl)-propylcarbamoyl]-6-phenyl-hexanoic acid::CHEMBL349099

SMILES C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccccc1)CC(O)=O)C(C)(C)C)c1ccccc1

InChI Key InChIKey=YXFLQXXMKGQVQR-BPUDTRNYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097253   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097253((R)-3-(((S)-3,3-dimethyl-1-oxo-1-((S)-1-phenylethy...)
Affinity DataIC50:  50nMAssay Description:Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097253((R)-3-(((S)-3,3-dimethyl-1-oxo-1-((S)-1-phenylethy...)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097253((R)-3-(((S)-3,3-dimethyl-1-oxo-1-((S)-1-phenylethy...)
Affinity DataIC50:  5.37E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097253((R)-3-(((S)-3,3-dimethyl-1-oxo-1-((S)-1-phenylethy...)
Affinity DataIC50:  2.80E+3nMAssay Description:Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed