BDBM50097981 (R)-4-((R)-4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester::CHEMBL353630

SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@@H]1CO)n1cc(-c2ccccc2)c2c(N)ncnc12

InChI Key InChIKey=LIDZEPDSSZLIPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097981   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097981((R)-4-((R)-4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50: 130nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed