BDBM50097996 CHEMBL168560::[(R)-4-((S)-4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-pyrrolidin-2-yl]-methanol

SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)[C@H]1CN[C@@H](CO)C1

InChI Key InChIKey=CBMZHRLWBJZWAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097996   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097996([(R)-4-((S)-4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50: 130nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed