BDBM50098292 5-Phenyl-2-([1,1';4',1'']terphenyl-4-sulfonylamino)-pent-4-ynoic acid::CHEMBL11188

SMILES OC(=O)C(CC#Cc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NDCGWDYXJPEWRR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098292   

Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098292(5-Phenyl-2-([1,1';4',1'']terphenyl-4-sulfonylamino...)
Affinity DataIC50: 29nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloprotease-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50098292(5-Phenyl-2-([1,1';4',1'']terphenyl-4-sulfonylamino...)
Affinity DataIC50: 58.9nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50098292(5-Phenyl-2-([1,1';4',1'']terphenyl-4-sulfonylamino...)
Affinity DataIC50: 59nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloprotease-13 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098292(5-Phenyl-2-([1,1';4',1'']terphenyl-4-sulfonylamino...)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloprotease-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098292(5-Phenyl-2-([1,1';4',1'']terphenyl-4-sulfonylamino...)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloprotease-1 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed