BDBM50098324 9-(4-{2-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-benzoimidazol-1-yl}-butyl)-9H-fluorene-9-carboxylic acid (2,2,2-trifluoro-ethyl)-amide::CHEMBL168216

SMILES Cc1nc2c(NC(=O)c3ccccc3-c3ccc(cc3)C(F)(F)F)cccc2n1CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc12

InChI Key InChIKey=PIGGVVZLWRHKDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098324   

TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098324(9-(4-{2-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...)
Affinity DataIC50:  0.150nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098324(9-(4-{2-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of human Microsomal Triglyceride Transfer Protein, (triglyceride transfer assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed