BDBM50098389 1-hydroxy-2-(1H-imidazol-5-yl)ethane-1,1-diyldiphosphonic acid::2-(4-imidazole)-1-hydroxy-ethane-1,1-bisphosphonate::CHEMBL301247::[1-Hydroxy-2-(1H-imidazol-4-yl)-1-phosphono-ethyl]-phosphonic acid::[1-Hydroxy-2-(3H-imidazol-4-yl)-1-phosphono-ethyl]-phosphonic acid
SMILES OC(Cc1cnc[nH]1)(P(O)(O)=O)P(O)(O)=O
InChI Key InChIKey=QJYHEVLLGQDDSN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50098389
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 309nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Negative logarithm of inhibitory concentration against bone resorptionMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase).More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign
Curated by ChEMBL
University of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair