BDBM50098523 4-(4-Chloro-benzylsulfanyl)-thieno[2,3-c]pyridine-2-carboxylic acid amide::CHEMBL269570

SMILES NC(=O)c1cc2c(SCc3ccc(Cl)cc3)cncc2s1

InChI Key InChIKey=NXPULJKXDBZNKI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098523   

TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098523(4-(4-Chloro-benzylsulfanyl)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 340nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098523(4-(4-Chloro-benzylsulfanyl)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 690nMAssay Description:In vitro potency against TNF alpha induced expression of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular cell adhesion protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098523(4-(4-Chloro-benzylsulfanyl)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro potency against TNF alpha induced expression of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed