BDBM50098546 (R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL283065

SMILES COc1cccc(OC)c1-c1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12

InChI Key InChIKey=CCSCYJFJDDPPKK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50098546   

Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]5-HT from rat 5-hydroxytryptamine 7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor was determined using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]5-HT from rat 5-HT7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  554nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  554nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  2.03E+3nMAssay Description:Displacement of [3H]raclopride from human dopamine receptor D2A expressed in mouse Ltk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed