BDBM50098756 1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(5-chloro-8-ethoxy-quinolin-7-ylsulfanyl)-phenyl]-propenone::CHEMBL19712

SMILES CCOc1c(Sc2ccc(\C=C\C(=O)N3CCN(CC3)C(C)=O)cc2Cl)cc(Cl)c2cccnc12

InChI Key InChIKey=GZUBGTRIHHDYOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098756   

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098756(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(5-chlor...)
Affinity DataIC50: 580nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed