BDBM50098761 6-{4-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-2-chloro-phenylsulfanyl}-2,3-dihydro-benzo[1,4]dioxine-2-carboxylic acid::CHEMBL280660

SMILES CC(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Sc2ccc3OC(COc3c2)C(O)=O)c(Cl)c1

InChI Key InChIKey=JKIWMIGBZFKLHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098761   

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098761(6-{4-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propenyl]-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed