BDBM50098762 1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1-ethyl-1H-indol-7-ylsulfanyl)-phenyl]-propenone::CHEMBL19390

SMILES CCn1ccc2cccc(Sc3ccc(\C=C\C(=O)N4CCN(CC4)C(C)=O)cc3Cl)c12

InChI Key InChIKey=IBJIONZZKQZZDE-CSKARUKUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098762   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098762(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1-ethyl...)
Affinity DataIC50:  130nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (120-140)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed