BDBM50099613 CHEMBL3356958

SMILES O=C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)n1ccnc1

InChI Key InChIKey=PTKAINQTOAZJAM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099613   

TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50099613(CHEMBL3356958)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MAGL expressed in HEK293 cells using 2-AG as substrate assessed as remaining activity at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50099613(CHEMBL3356958)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50099613(CHEMBL3356958)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099613(CHEMBL3356958)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50099613(CHEMBL3356958)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed