BDBM50099644 3-(4-Isopropyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carboxylic acid cyclohexylamide::CHEMBL45362

SMILES CC(C)N1CCN(Cc2c(nc3ccccc3c2C(=O)NC2CCCCC2)-c2ccccc2)CC1

InChI Key InChIKey=KULZXADAJUBWTD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099644   

TargetSubstance-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099644(3-(4-Isopropyl-piperazin-1-ylmethyl)-2-phenyl-quin...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099644(3-(4-Isopropyl-piperazin-1-ylmethyl)-2-phenyl-quin...)
Affinity DataKi:  226nMAssay Description:Binding affinity towards human mu-opioid receptors in CHO (Chinese hamster ovary) cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099644(3-(4-Isopropyl-piperazin-1-ylmethyl)-2-phenyl-quin...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed