BDBM50099700 CHEMBL51776::N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo-9,10-dihydro-phenanthren-2-yl]-succinamic acid methyl ester

SMILES COC(=O)CCC(=O)Nc1ccc-2c(c1)C(=O)C(=O)c1cc(NC(=O)CCC(=O)OC)ccc-21

InChI Key InChIKey=GKNYSTDFDJPKOW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50099700   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory concentration against Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099700(N-[7-(3-Methoxycarbonyl-propionylamino)-9,10-dioxo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed