BDBM50099814 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide::4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide::CHEMBL298875
SMILES COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1
InChI Key InChIKey=UBVYCNOXGQYSRQ-UHFFFAOYSA-N
Data 13 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50099814
Affinity DataKi: 1.60nMAssay Description:Binding affinity for dopamine receptor D3 expressed in Sf9 cells using [125I]IABN the radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Ability to displace [3H]spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Ability to displace [3H]spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Wake Forest University School of Medicine
Curated by ChEMBL
Wake Forest University School of Medicine
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Binding affinity for sigma-1 receptor measured on guinea pig brain membranes using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity for dopamine receptor D2 long expressed in Sf9 cells using [125I]IABN radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Ability to displace [3H]spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human cloned dopamine receptor D2S expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Displacement of [3H]spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Displacement of [3H]spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nMAssay Description:Displacement of [3H]SCH-23390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Displacement of [3H]SCH-23390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranesMore data for this Ligand-Target Pair